She works mainly in medical retina. For almost 40 years she has been part of the Ophthalmology Unit of IRCCS San Raffaele Hospital in Milan, where she heads a functional unit and, since 1997, the Medical Retina and Vascular Diseases Service.

She specialises in retinal vascular diseases, such as diabetic retinopathy and venous and arterial occlusions, and in macular diseases. Since 2002 she has been adjunct professor of Ophthalmology at Vita-Salute San Raffaele University, and in 2020 she obtained the Italian national qualification as associate professor.

She has been an investigator in numerous international multicentre clinical trials and was president of the Italian Retina Society in 2021–2022. She has co-authored 4 books and more than 100 scientific publications.